Drug interactions may well modify how your remedies do the job or boost your hazard for really serious side effects. This doc won't have all achievable drug interactions.

It's soluble in h2o and freely soluble in alcohol. The molecular weight is 320.88. Its molecular system is C17H20N2S•HCl, and it's got the following chemical composition.

To assist stop withdrawal, your health practitioner may well lower your dose slowly and gradually. Withdrawal is a lot more likely In case you have made use of this medication for some time (more than a few weeks) or in large doses. Notify your health care provider or pharmacist right away For those who have withdrawal.

Carcinogenicity, mutagenicity, and fertility studies haven't been done with Promethazine with Codeine Oral Solution; on the other hand, posted facts is readily available for the individual active elements.

This medication can dry up and thicken mucus as part of your lungs, rendering it tougher to breathe and obvious your lungs. That will help avoid this outcome, consume lots of fluids Unless of course or else directed by your medical professional.

The consequences of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are advanced.

Promethazine with Codeine Oral Alternative need to be made use of with warning in sufferers with bone-marrow depression. Leukopenia and agranulocytosis happen to be reported, ordinarily when promethazine has actually been Employed in association with other recognized marrow-poisonous brokers.

The causal job of opioids in the scientific syndrome of hypogonadism is unknown as the many medical, Actual physical, Way of living, and psychological stressors which will affect gonadal hormone degrees have not been adequately managed for in scientific tests executed thus far [see ADVERSE REACTIONS (6)].

If you use opioid medicine while you're Expecting, your child could become depending on the drug. This may cause lifetime-threatening withdrawal signs or symptoms in the baby immediately after it's born. Babies born dependent on opioids may need medical procedure for several months.

Promethazine VC with Codeine can slow or quit your respiration, and Demise may well occur. Somebody caring for it is best to seek unexpected emergency health care attention if you have sluggish respiratory with extended pauses, blue coloured lips, or For anyone who is challenging to wake up.

A perhaps deadly symptom intricate occasionally often called Neuroleptic Malignant Syndrome (NMS) continues to be reported in Affiliation with promethazine HCl by itself or in combination with antipsychotic medicines.

Codeine: Narcotic analgesics, including codeine, exert their Main effects on the central anxious process and gastrointestinal tract. The analgesic outcomes of codeine are as a consequence of its central motion; on the other hand, the exact internet sites of motion have not been established, plus the mechanisms involved look like really complicated.

Codeine provides respiratory depression by direct motion on brain stem respiratory centers. The respiratory melancholy will involve a discount while in the responsiveness on the Promethazine With Codeine Products For Sale online Mind stem respiratory facilities to both of those boosts in carbon dioxide rigidity also to electrical stimulation.

The effects of concomitant use or discontinuation of cytochrome P450 3A4 inducers, 3A4 inhibitors, or 2D6 inhibitors with codeine are complex.